How Breast Cancer Happens

Breast profile:
A Ducts
B Lobules
C Dilated section of duct to hold milk
D Nipple
E Fat
F Pectoralis major muscle
G Chest wall/rib cage
Enlargement
A Normal duct cells
B Basement membrane
C Lumen (center of duct)

The breast is a gland designed to make milk. The lobules in the breast make the milk, which then drains through the ducts to the nipple.
Like all parts of your body, the cells in your breasts usually grow and then rest in cycles. The periods of growth and rest in each cell are controlled by genes in the cell's nucleus. The nucleus is like the control room of each cell. When your genes are in good working order, they keep cell growth under control. But when your genes develop an abnormality, they sometimes lose their ability to control the cycle of cell growth and rest.
Breast cancer is an uncontrolled growth of breast cells.
Cancer has the potential to break through normal breast tissue barriers and spread to other parts of the body. While cancer is always caused by a genetic "abnormality" (a "mistake" in the genetic material), only 5–10% of cancers are inherited from your mother or father. Instead, 90% of breast cancers are due to genetic abnormalities that happen as a result of the aging process and life in general.
While there are things every woman can do to help her body stay as healthy as possible (such as eating a balanced diet, not smoking, minimizing stress, and exercising regularly), breast cancer is never anyone's fault. Feeling guilty, or telling yourself that breast cancer happened because of something you or anyone else did, is counterproductive.
Source ; breastcancer.org

What Is Metastatic Breast Cancer?

The most frightening words imaginable for any woman are those when she is told that she has breast cancer. The morbid thoughts run through her head and the fear is overwhelming. Now she must endure medical treatments and examinations for several months as begins her battle against this disease.

Cancer is defined by four different stages and metastatic breast cancer is defined as stage 4 and it means that the cancer has spread beyond the breast and underarm lymph nodes to other part of the body. Another way to explain this is that the cancer cells have migrated and are now growing outside of the original tumor.

Women who have stage IV breast cancer usually receive chemotherapy and or hormonal therapy to destroy cancer cells and control the disease. They may have surgery or radiation therapy to control the cancer in the breast. Radiation may also be useful to control tumors in other parts of the body. The symptoms of metastatic breast cancer varies depend on where the cancer is and how large it is.

The most common places for breast cancer to spread are within the breast or to the nearby chest wall or to the liver, lungs, or bones. Common symptoms include a lump in your breast or on your chest wall, bone pain, or shortness of breath. It is also possible that you will not have any symptoms and that the only way to keep yourself healthy is to be proactive and to take an active role in your health care. It may be necessary to have continuous laboratory tests and x-rays to determine whether or not the cancer has spread.

Work with your doctors to plan your medical treatments and to be a partner in your health care. Your doctors will consider where the cancer is located and what type of cancer treatments you had in the past. Your wishes and quality of life are also important factors.

Treatment choices may include surgery, medicines like chemotherapy or hormone therapy, and radiation. Sometimes a mix of these treatments is used and there can be side effects. Your doctor can tell you what problems to expect and can help you find ways to manage and live with them during the treatment phase.

There may come a time with metastatic breast cancer when you make a decision that quality of life is more important than quantity. If the medical treatments are not working and the effects of them are more devastating than the actual disease, you may have a choice to make.

Some people make the decision after talking to their family, friends and doctors to shift the focus of their treatments from attempting to cure the disease to staying comfortable and enjoying life. The care at this point is entirely focused on providing symptom relief as well as support for you and your family so that everyone can make the most of the time remaining.

The final choice for your care after you have been diagnosed with metastatic breast cancer if yours! And, you should make informed decision after talking to your doctors and family members. Medical advances in this area are moving forward every day and you never know when the cure will be found.
By: Samantha Kay

About the Author:

For more information on breast cancer visit http://www.breastcanceranalysis.com - a website that specializes in breast cancer related information and resources including information on metastatic breast cancer.

Read more articles by: Samantha Kay

Article Source: www.iSnare.com

Breast Exam (Breast Cancer)

Breast Cancer The Cure

There is no known cure for breast cancer. More than 1.5 million people will be diagnosed with breast cancer this year worldwide. Scientists don't know why most women get breast cancer, yet breast cancer is the most frequent tumor found in women the world over. A woman who dies of breast cancer is robbed of an average of nearly 20 years of her life. Breast cancer knows no social boundaries. It’s a disease that can affect anyone. Some prominent women who’s lives that have been touched by breast cancer include Jill Eikenberry actress age 52; Peggy Fleming age 49 figure skater; Kate Jackson age 50 (Charlies Angels); Olivia Newton-John age 50 actress singer; Nancy Reagan age 77 former first lady; Melissa Etheridge age 43 singer; and the beautiful Suzanne Summers actress. These high rates of breast cancer are not acceptable to the women of the world and must be met with scientific research that provides results.

Despite over a decade of research, and more than $1.7 billion spent, hundereds of women worldwide are dying from breast cancer every day. Yet doctors don’t know how breast cancer starts or how to cure it. Doctors are still approaching treatment for breast cancer in the same old fashioned ways: surgery, radiation, and chemotherapy. Barbarick treatments…And scientists keep doing the same old redundant research that’s simply not working. It doesn’t have to be that way. Gen Cells Cures is a scientific biotechnology company that is focused on a cure for breast cancer. The company is dedicated to curing breast cancer before it’s too late for you. We’re not interested in a cure in five, ten, or twenty years from now. We want your cure for breast cancer within a year or two. We don’t want you to have to under go surgery, radiation, chemotherapy or take toxic drugs.

Why Gen Cells Cures? You can search the medical journals; you can search the internet until your blue in the face. You will find the same old news which is no new news about breast cancer research and treatments. Breast cancer research is locked up in a black whole. Gen Cells Cures is approaching the cure for breast cancer from different angles and using tomorrow’s scientific technologies today. Our expertise is in stem cell research and genomics. Malfunctioning stem cells have already been linked to the development of breast cancer. We’re not talking about using generic stem cells from an egg and sperm cell. There is no genetic match for you with the politically controversial generic stem cells that are always in the news. The isolation of cancer stem cells, coupled with our understanding of genetic mutations causing cancer, and our knowledge of genomics will result in ways to eliminate cancer cells while sparing normal breast tissues.

Genetics and Breast Cancer

People will tell you to accept what you can’t change…Your genetics, your genes, the genes your mother and father handed you when you were born that came with their particular genetic make-up. Most inherited cases of breast cancer have been associated with two genes: BRCA1 and BRCA2. The past five years has been a period of unparalleled discovery in the field of genetics, genomics, and stem cell research, but these discoveries are not being applied to breast cancer treatments. A job that Gen Cells Cures definitely wants to get our hands dirty in. Recently researchers have found that by blocking a gene called beta1-integrin the growth of tumor cells can be stopped. When this gene was removed the tumor cells quit growing. You don’t have to accept the genes that you were given at birth. Gen Cells Cures will be able to manipulate your genes to cure your breast cancer.

Our Cancer Stem Cell and Genomics Program will bring together the top scientific minds in the world under one tin roof to maximize the use of diverse approaches to the understanding of cancer genomics fused with stem cell solutions. Gen Cells Cures isn’t looking for a multi-million dollar biomedical research center like the Stowers Institute in Kansas City, which is a medical center to be admired. A rented tin shack will do just fine. Of course, we would accept hand-me down michroscopes from the Stoweres (billionaires who bought their own multi-million dollar biomedical research center) if they would be gracious enough to grant them to us or we would accept a small prime the pump check to move forward with our research. The Stowerses and all the scientists from the Stowers Institute have an open invitation to visit our lab in the Caribbean. What we are looking for is a cure for breast cancer to stop the humiliation, pain and suffering this menace to society causes millions of women and thousands of men worldwide, and not a new biomedical center… Every dollar invested with us goes into pure medical research and equipment. The same offer goes out to all the millionaires and especially the billionaires of the world. People that come to mind are: Paul Allen, Bill and Melinda Gates, Jon Huntsman, William and Alice Goodman, Ann Lurie, Jamie and Karen Moyer, Harold C. Simmons, Alfred Mann, Sumner M. Redstone, Michael Milton and the Palm beach billionaires, there are simply too many to mention. The combined wealth of the three Microsoft billionaires alone is more than ten times the amount spent by the U.S. Federal Government on research to fight cancer and other deadly diseases. We know we’re in the wrong business to become billionaires ourselves. This kind of biotechnology has never produced even one billionaire. It’s the cure for breast cancer that we want.

Simply put the cancer research organizations are funding the wrong researchers. It’s time to go outside the normal research channels. Do something different. The same story year after year after year and no cure. These unmotivated researchers just aren’t getting results. Let someone else have a shot at it. It’s time to try something new and different. A different approach. There are races for the cure, golf tournaments for the cure, there are walks for the cure, there are foundations for the cure. These foundations have been funding the same ineffective research for more than twenty years now. These foundations have been betting on the wrong horse. Joining the crusade won’t help if the research being done doesn’t take on a twenty-first century scientific approach. It’s been time to move forward scientifically for five years now. But today’s breast cancer researchers are stuck in a twentieth century mind-set. The Excuse is someday we’ll find the cure, but someday doesn’t help today’s victims of breast cancer. We need top notch scientific action today.

The genetics are out of the bottle and stem cell research is moving forward whether the U.S. government likes it or not. Gen Cells Cures has moved off-shore to the Caribbean to avoid the political controversy over stem cell research. I am sure you won’t mind a walk on the beach with me to talk about your cure for your breast cancer. Once we have the cure we can take the cure from the bench to the patient without a long and costly wait for FDA approval. There are many advantages to not having big brother breathing down your neck. The governments of the United States and Western countries have nothing to offer except road blocks, red tape and detours. Our patients don’t have time for political smoke and mirrors. With a little luck we could have your cure before the time comes that you need that dreaded surgery and chemo.

Our gifted world-class researchers are visionary and have been schooled in winning and have courage, creativity, can-do attitudes, burning desires, unfaltering belief and an obsession that they will be there first. By first we mean years ahead of the other biotechnology companies. Like determined, fighting NASCAR drivers our scientists are living to take the chequered flag of biotech and win the coveted race for the cure for breast cancer.

Focused on breakthrough discoveries, Gen Cells Cures nurtures a culture that encourages high standards of excellence, original thinking, hard work and a willingness to take risks. Our world-renowned scientists believe in themselves and its belief that gets us there. The company will seek to develop a work environment that is results focused and team-orientated. We compete against time. Though we compete intensely we maintain high ethical standards and trust and respect for each other. Quality is the cornerstone of all our activities. We seek the highest quality information, decisions and people. Our success depends on superior scientific innovation. We see the scientific method as a multi-step process which includes designing the right experiment, collecting and analyzing data and rational decision making. It is not subjective or emotional but rather a logical, open and rational process.

Our success comes from one simple fact; we are committed to being a science-based, patient-driven company, driven by that one special breast cancer patient…you.

Gen Cells Cures lost most of our one million dollar start-up money in offshore bank scandal and currency devaluation last year. We are now actively pursuing financial support. Unfortunately, the Gen Cells Cures team is made up of great scientific minds and not great marketers, salesmen, or fund raisers. Yes, we are looking for a millionaire or billionaire without a cause to support our work, but if you are not our wealthy saviour, we welcome any help, be it financial or a donation of your time. The scientific team is on stand-by. What we’re lacking is the funding to go forward. We could use motivated salesmen to sell our research, fund raisers, skilled internet marketers or someone just to pass out flyers or mail out promotional material. We could use help from the media with publicity stories, ads and promotions to get the word out. We are particularly interested in looking for assistance from the billionaires of the world; there are approximately 600 in the world. Billionaires like Sergey Brin and Larry Page (Google billionaires), Rupert Murdoch, Ted Turner, and Oprah Winfrey and others who control the media could get our life-saving message to the world fast. We are also hoping that some of my celebrities friends will come forward and spread their wings to help support our breast cancer research: Steven Seagal, Charlie Sheen, Wesley Snipes, Danny Glover, Erik Estrada, Tom Arnold, Dolph Lundgren, Roger Clinton, Bill Clinton, Usher, Hulk Hogan, Ivana Trump, John Secada, Sylvester Stalone, Arnold Schwarzenegger, Mike Reno, Richard Branson, Cindy Crawford, Cher, Demi Moore, Michelle Pfeiffer, and other stars that I have had the good fortune of meeting in person and others celebrities that I hope to meet in the future. (Photos of Gerald and the stars can be viewed at his promotional group listed below.) I am waiting to get my photo with Suzanne Summers!

Gen Cells Cure offers more than hope. We can do the job. If you’re going to eradicate cancer you have to have the right people doing the right research. One thing is for sure. We couldn’t do any worse than what the scientists before us have done. Which is virtually nothing! Help us alleviate the pain and suffering. Together, with your help, we can cure breast cancer.
by: Gerald Armstrong
Article by Gerald Armstrong- scientist0707@yahoo.com
Gerald is the owner of Gen Cells Cures
Visit his group for information about “The Cure” for incurable diseases and aging.
Group address http://www.msnusers.com/cures
About the Author
Hello, Ladies and Gentlemen, I am Gerald Armstrong the owner of Gen Cells Cures a biotech dedicated to finding “The Cure” for incurable diseases and aging. Introducing to the world, the miracle of private, personalized medical research for the individual. I am passionate about molecular biology and what we can do with science to find “The Cure” for those of you suffering from aging and incurable diseases. http://www.msnusers.com/cures

Breast cancer for beginners

by: Mansi gupta
Introduction
Because of the social changes, which has brought increased number of workingwoman and hence delayed childbearing, there has been a steep rise in the number of breast cancer patients in the last few decades. But as the incidence of the patients has risen so has raised the modality of treatments and the success rates. Also scientists have devised methods by which the cancer can be detected in an early stage and it has been convincingly proved that early detection and treatment bears a better prognosis than the later stage.

Myths
There are many myths attached to breast cancer. Some think that any lump in breast is a breast cancer but to the contrary most of them are benign. Similarly it was a popular belief earlier that breast-feeding decreases one’s risk of the cancer but that has been now found to be untrue. Some say that mammography makes the breast cancer widespread but it’s not true. Similarly there are many other myths, which need to be cleared in mind of the general mass for the proper detection and management of the tumor.

Early detection
Breast cancer can be detected in an early stage if women are taught to self-examine their breast. In case of detection of any breast lump or of any slightest suspicion, mammography should be done to rule out any tumor. Mammography is a good tool to diagnose this type of cancer.

Statistics
The incidence of breast cancer is increasing at an alarming rate. It is said that every 2-3 minutes one American woman is diagnosed a breast cancer.

Cause
Although the cause is not fully understood but it is hypothesized that there are various factors such as genetic and environmental. The environmental factors are increased age, obesity, smoking and having the first child at late age.

Diagnosis
The findings that denote a cancer are single, non-tender and firm to hard mass with ill-defined margins. This can be later confirmed by mammography and biopsy. After the cancer has been diagnosed staging is done to find out the best treatment option as well as the prognosis.

Management
The management of breast cancer rests basically on two things. The first is the treatment and second is the counseling. The treatment can further be divided into three: medical, radiation, and surgery. The medical treatment consists of drugs such as tamoxifen, which is an anti estrogen, aromatase inhibitors such as aminoglutethimide and monoclonal antibodies such as trastuzumab. But similar to other drugs they have their own side effects profile. The side effects associated with tamoxifen are increased vaginal bleeding, endometrial cancer and cataracts. The aromatase inhibitors have the side effects of leg cramps, jaundice and weight gain while the monoclonal antibodies may cause sterility or certain birth abnormalities.
Generally the radiation and surgery are the modalities, which are needed for the treatment to ward off the body of the cancerous growth.

Counseling
This is one of the most important parts of the treatment both before and after the surgery. The patients are to be taught that this is only another disease, which has treatment available, and persons can lead a normal life after that.

Latest research
Latest research is being done on both the surgery and the medicine. For the surgery, surgeons are trying to find out the best way of surgery so that post surgery the patients have minimal disabilities. Similar medicines with lesser side effects are being researched.
by: Mansi gupta
About the Author
Mansi gupta writes about breast cancer topics.

BREAST CANCER

Breast cancer occurs when cells in the breast begin to grow out of control enabling them to invade nearby tissues or spread throughout the body. Collections of these out of control tissues are called tumors. However, not all breast tumors are considered cancerous since certain types of large cells just cannot be spread or threaten a person’s life and this kind of tumor is called benign tumor. On the other hand, the tumors that can spread all throughout the body or invade nearby tissues are considered cancerous cells and are malignant. Cancer cells usually comes from either ducts or glands in the breast that is why it may take months or even years for a tumor to be notice in the breast. Breast tumors are screened with the use of mammograms that are rather accurate in screening tumor or cancer cells.
Women are much prone to develop breast cancer that men. Only 1% to 2% of men have been known to have cases of breast cancer. The early onset of menstruation in women at the age of 12 increases the risk for a breast cancer on the other hand an early menopausal period may reduce the risk of breast cancer. The risk for women to have breast cancer increases with age in fact a study shows that women over 50 are more likely to develop breast cancer. Nevertheless, the incidence of breast cancer among younger women is also increasing in an alarming rate that is why more women of ages 20s to 30s have subjected themselves to be diagnosed.
Breast cancer is not only acquired but also can be inherited. For women who have genetic mutation such as BRCA1 or BRCA2 has an 80% risk of developing breast cancer. Women who have first-degree relative diagnosed to have breast cancer increase their risk of also acquiring breast cancer. Moreover, women with first-degree relative that are diagnosed to have breast cancer before menopause increase the risk for them in acquiring breast cancer.
Some factors contribute to the occurrence of breast cancer and these are as follows: smoking, alcohol and radiation exposure. Women who are smoking will increase their chances to have breast cancer. Aside from that, high intakes of alcohol have been found to be a source of breast cancer. Radiation exposure is another factor that contributes to breast cancer. Studies have shown that women as well as children who have undergone high-dose radiation therapy have a much higher chance of having breast cancer.
by: Khloe Penelope Cruise
About the Author
She loves to read and write poems. A romantic at heart.